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Lecythophora mutabilis prosthetic valve endocarditis in a diabetic patient.
- Source :
-
Medical mycology [Med Mycol] 2007 Aug; Vol. 45 (5), pp. 463-7. - Publication Year :
- 2007
-
Abstract
- While dematiaceous (dark-walled) fungi are ubiquitous in the environment, their involvement in invasive human infections has rarely been reported. However, these organisms have been identified as potential emerging pathogens, particularly among immunocompromised hosts. We describe a diabetic patient with Lecythophora mutabilis prosthetic valve endocarditis who was treated surgically, as well as with amphotericin B lipid complex and voriconazole, which were subsequently followed by prolonged voriconazole suppressive therapy. To the best of our knowledge, our patient is the first reported survivor of L. mutabilis prosthetic valve endocarditis.
- Subjects :
- Amphotericin B therapeutic use
Antifungal Agents therapeutic use
Aortic Valve surgery
Ascomycota classification
Ascomycota genetics
Drug Combinations
Endocarditis drug therapy
Endocarditis surgery
Heart Valve Prosthesis adverse effects
Humans
Male
Middle Aged
Molecular Sequence Data
Mycoses drug therapy
Mycoses microbiology
Mycoses surgery
Phosphatidylcholines therapeutic use
Phosphatidylglycerols therapeutic use
Prosthesis-Related Infections drug therapy
Prosthesis-Related Infections surgery
Pyrimidines therapeutic use
Sequence Analysis, DNA
Treatment Outcome
Triazoles therapeutic use
Voriconazole
Ascomycota isolation & purification
Diabetes Complications
Endocarditis microbiology
Heart Valve Prosthesis microbiology
Prosthesis-Related Infections microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1369-3786
- Volume :
- 45
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Medical mycology
- Publication Type :
- Academic Journal
- Accession number :
- 17654274
- Full Text :
- https://doi.org/10.1080/13693780701386007