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Mitotic motors: kinesin-5 takes a brake.
- Source :
-
Current biology : CB [Curr Biol] 2007 Jul 17; Vol. 17 (14), pp. R544-7. - Publication Year :
- 2007
-
Abstract
- A kinesin-5-dependent 'sliding filament' mechanism is commonly used to actively push apart the poles during mitotic spindle assembly and elongation, but a recent study now shows that, in C. elegans, kinesin-5 is deployed as a brake to slow down spindle-pole separation.
Details
- Language :
- English
- ISSN :
- 0960-9822
- Volume :
- 17
- Issue :
- 14
- Database :
- MEDLINE
- Journal :
- Current biology : CB
- Publication Type :
- Academic Journal
- Accession number :
- 17637353
- Full Text :
- https://doi.org/10.1016/j.cub.2007.05.030