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Infectivity, oncogenicity and transforming ability of BK virus and BK virus DNA.

Authors :
van der Noordaa J
Source :
The Journal of general virology [J Gen Virol] 1976 Mar; Vol. 30 (3), pp. 371-3.
Publication Year :
1976

Abstract

The human papovavirus, BK, appeared weakly oncogenic in newborn hamsters and was able to induce in vitro transformation of rat kidney cells. The infectivity of BK virus DNA was determined by employing the DEAE-dextran method. In human embryonic cells the infectivity was approx. 10(5) p.f.u./mug of DNA. The transforming ability of BK virus in primary rat kidney cells was measured by employing the calcium method and appeared to vary from 1 to 10 foci per mug of DNA.

Details

Language :
English
ISSN :
0022-1317
Volume :
30
Issue :
3
Database :
MEDLINE
Journal :
The Journal of general virology
Publication Type :
Academic Journal
Accession number :
176315
Full Text :
https://doi.org/10.1099/0022-1317-30-3-371