Back to Search
Start Over
Does implantation of sonomicrometry crystals alter regional cardiac muscle function?
- Source :
-
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography [J Am Soc Echocardiogr] 2007 Dec; Vol. 20 (12), pp. 1407-12. Date of Electronic Publication: 2007 Jul 02. - Publication Year :
- 2007
-
Abstract
- Background: Sonomicrometry is a gold standard in experimental studies on myocardial motion. However, limited information exists regarding mechanical and biochemical changes produced by sonomicrometry crystal (SC) insertion into the myocardial wall.<br />Methods: In 10 open-chest pigs, we implanted SCs into the inner half of apical anterior and midposterior regions. Longitudinal strains (systolic lengthening, end-systolic, peak shortening, and postsystolic shortening strains) and strain rate (SR) measurements (peak systolic ejection and early and late diastolic SRs) were obtained by Doppler SR echocardiography along with troponin I levels measured from peripheral blood before and after SC insertion.<br />Results: SR and strain parameters did not change significantly after SC implantation. Troponin I levels increased significantly from less than 0.010 to 0.129 +/- 0.138 microg/L (P < .005) after SC implantation.<br />Conclusions: Our study demonstrates that despite biochemical evidence of myocardial injury, carefully implanted SCs do not alter systolic or diastolic regional myocardial function assessed by Doppler echocardiography.
Details
- Language :
- English
- ISSN :
- 1097-6795
- Volume :
- 20
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
- Publication Type :
- Academic Journal
- Accession number :
- 17604963
- Full Text :
- https://doi.org/10.1016/j.echo.2007.04.010