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[Management of Alzheimer disease].
- Source :
-
Presse medicale (Paris, France : 1983) [Presse Med] 2007 Oct; Vol. 36 (10 Pt 2), pp. 1500-10. Date of Electronic Publication: 2007 Jun 29. - Publication Year :
- 2007
-
Abstract
- Management of Alzheimer disease is based on drug and nondrug treatments. Specific drug treatment includes acetylcholinesterase inhibitors and memantine. They show moderate efficacy superior to that of placebo for global condition, cognitive disorders, need for care, and behavioral problems, but do not prevent further decline. These treatments remain underused. The efficacy of psychotropic drugs (antidepressants, neuroleptics, and antipsychotic agents) in treating behavioral problems is not well documented. Nondrug activities and interventions have not been sufficiently evaluated scientifically. These involve interventions against the consequences of the disease (loss of autonomy, malnutrition) and helping patients' family caregivers. Among these activities, the best evaluated and most interesting are: educational programs for caregivers, occupational therapy at home, and interventions at home by nurses specially trained as case managers.
- Subjects :
- Aged
Alzheimer Disease diagnosis
Alzheimer Disease drug therapy
Alzheimer Disease nursing
Animals
Antipsychotic Agents therapeutic use
Caregivers education
Case Management
Disease Models, Animal
Donepezil
Dopamine Agents therapeutic use
Excitatory Amino Acid Antagonists therapeutic use
Follow-Up Studies
Forecasting
Health Education
Humans
Indans therapeutic use
Memantine therapeutic use
Mental Disorders drug therapy
Meta-Analysis as Topic
Nootropic Agents therapeutic use
Occupational Therapy
Piperidines therapeutic use
Practice Guidelines as Topic
Psychotropic Drugs therapeutic use
Randomized Controlled Trials as Topic
Time Factors
Alzheimer Disease therapy
Cholinesterase Inhibitors therapeutic use
Subjects
Details
- Language :
- French
- ISSN :
- 0755-4982
- Volume :
- 36
- Issue :
- 10 Pt 2
- Database :
- MEDLINE
- Journal :
- Presse medicale (Paris, France : 1983)
- Publication Type :
- Academic Journal
- Accession number :
- 17601697
- Full Text :
- https://doi.org/10.1016/j.lpm.2007.04.028