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International workshop on immune tolerance induction: consensus recommendations.
- Source :
-
Haemophilia : the official journal of the World Federation of Hemophilia [Haemophilia] 2007 Jul; Vol. 13 Suppl 1, pp. 1-22. - Publication Year :
- 2007
-
Abstract
- Although immune tolerance induction (ITI) has been used for 30 years to eliminate inhibitors and restore normal factor pharmacokinetics in patients with hemophilia, there is a paucity of scientific evidence to guide therapeutic decision-making. In an effort to provide direction for physicians and hemophilia treatment center staff members, an international panel of hemophilia opinion leaders met to develop consensus recommendations for ITI in patients with severe and mild hemophilia A and hemophilia B. These recommendations draw on the available published literature and the collective clinical experience of the group and are rated based on the level of supporting evidence.
- Subjects :
- Catheters, Indwelling
Child, Preschool
Cost-Benefit Analysis
Equipment Failure
Factor IX administration & dosage
Factor IX immunology
Factor IX pharmacokinetics
Factor VIII administration & dosage
Factor VIII immunology
Factor VIII pharmacokinetics
Hemophilia A immunology
Humans
Infant
Infections complications
Infections immunology
Meta-Analysis as Topic
Randomized Controlled Trials as Topic
Risk Factors
Treatment Failure
Blood Coagulation Factor Inhibitors immunology
Factor IX antagonists & inhibitors
Factor VIII antagonists & inhibitors
Hemophilia A therapy
Immunosuppression Therapy methods
Subjects
Details
- Language :
- English
- ISSN :
- 1351-8216
- Volume :
- 13 Suppl 1
- Database :
- MEDLINE
- Journal :
- Haemophilia : the official journal of the World Federation of Hemophilia
- Publication Type :
- Academic Journal
- Accession number :
- 17593277
- Full Text :
- https://doi.org/10.1111/j.1365-2516.2007.01497.x