Molecular characterization of bovine group A rotavirus G3P[3] strains.

Authors :: Ghosh S
Varghese V
Samajdar S
Sinha M
Kobayashi N
Naik TN
Source :: Archives of virology [Arch Virol] 2007; Vol. 152 (10), pp. 1935-40. Date of Electronic Publication: 2007 Jun 18.
Publication Year :: 2007
Abstract: During a surveillance study, four of 130 group A rotavirus strains, detected from diarrheic calves in Eastern India, exhibited G3P[3] specificities. Molecular characterization of VP7 and VP8(*) genes of one such strain [named as RUBV3 (RU: ruminant and BV: bovine)] revealed genetic relatedness to a G3P[3] simian strain, RRV, and RRV-related caprine strain GRV. Strain RUBV3 had VP6, NSP4 and NSP5 genes of bovine origin. Therefore, the present study provides evidence for multiple reassortment events involving ruminant and simian strains and, to our knowledge, is the first report of detection of bovine group A rotavirus strains with G3P[3] specificities.