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Development of a catalytic aromatic decarboxylation reaction.

Authors :
Dickstein JS
Mulrooney CA
O'Brien EM
Morgan BJ
Kozlowski MC
Source :
Organic letters [Org Lett] 2007 Jun 21; Vol. 9 (13), pp. 2441-4. Date of Electronic Publication: 2007 Jun 02.
Publication Year :
2007

Abstract

A palladium-catalyzed aromatic decarboxylation reaction has been developed. With electron-rich aromatic acids, the reaction proceeds efficiently under fairly mild conditions in good yields. The method was useful with complex functionalized substrates containing hindered carboxylic acids.

Details

Language :
English
ISSN :
1523-7060
Volume :
9
Issue :
13
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
17542594
Full Text :
https://doi.org/10.1021/ol070749f