[Depression as a side effect of alpha-interferon: mechanisms of development and criteria for experimental evaluation].

Authors :: Madzhumder IS
Kalenikova EI
Gorodetskaia EA
Siutkin VE
Source :: Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2007 Mar-Apr; Vol. 70 (2), pp. 75-8.
Publication Year :: 2007
Abstract: Possible mechanisms of the development of depression as a side effect of the a-interferon are reviewed. Methods used for the characterization of depressive states in experiment are considered.

Subjects :: Animals
Cytokines metabolism
Depressive Disorder metabolism
Depressive Disorder physiopathology
Fatty Acids metabolism
Humans
Interferon-alpha therapeutic use
Serotonin metabolism
Depressive Disorder chemically induced
Interferon-alpha adverse effects

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