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Carotid artery calcification on multislice detector-row computed tomography.
- Source :
-
Cerebrovascular diseases (Basel, Switzerland) [Cerebrovasc Dis] 2007; Vol. 24 (1), pp. 20-6. Date of Electronic Publication: 2007 May 22. - Publication Year :
- 2007
-
Abstract
- Background: To determine the underlying conditions that affect the degree of calcification of carotid arterial plaques, measured quantitatively using multidetector row computed tomography (MDCT), and to study the association of carotid calcification with clinical symptomatology.<br />Methods: We measured the calcification volume of stenotic lesions at the carotid bifurcation using MDCT in 84 consecutive patients who were scheduled to undergo carotid revascularization. These results were compared with the clinical and radiological characteristics of the patients.<br />Results: On MDCT, calcification in the carotid plaques was present in 78 patients (93%). Compared to the other patients, patients in the highest quartile of calcification volume (quartile 4) had higher serum creatinine levels (p < 0.001) and tended to have fewer symptomatic ischemic events in the territory of the affected carotid artery in the preceding 6 months (29 vs. 49%, p = 0.099); in particular, there were fewer transient symptoms (5 vs. 27%, p = 0.032) and symptoms possibly occurring due to local embolism (14 vs. 37%, p = 0.045). On ultrasound, plaque ulceration was less prevalent in patients in quartile 4 than in the remaining patients (5 vs. 29%, p = 0.026), although the severity of carotid stenosis was similar among all the quartiles.<br />Conclusions: Renal dysfunction was associated with enhanced carotid plaque calcification. Patients with severe carotid calcification were found to have a low risk of recent ischemic stroke, presumably due, in part, to a lower prevalence of emboligenic carotid ulceration. MDCT was valuable for the quantitative evaluation of carotid calcification.
- Subjects :
- Aged
Aged, 80 and over
Angiography, Digital Subtraction
Brain Ischemia etiology
Calcinosis complications
Calcinosis etiology
Carotid Stenosis complications
Carotid Stenosis etiology
Female
Humans
Kidney Failure, Chronic complications
Male
Middle Aged
Risk Assessment
Risk Factors
Severity of Illness Index
Ultrasonography, Doppler, Duplex
Calcinosis diagnostic imaging
Carotid Stenosis diagnostic imaging
Tomography, X-Ray Computed
Subjects
Details
- Language :
- English
- ISSN :
- 1015-9770
- Volume :
- 24
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Cerebrovascular diseases (Basel, Switzerland)
- Publication Type :
- Academic Journal
- Accession number :
- 17519540
- Full Text :
- https://doi.org/10.1159/000103112