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[Relevance of the toxoplasma IgG avidity test in the serological surveillance of pregnant women].

Authors :
Soula F
Fréalle E
Durand-Joly I
Dutoit E
Rouland V
Renard E
Houfflin-Debarge V
Subtil D
Camus D
Dei-Cas E
Delhaes L
Source :
Annales de biologie clinique [Ann Biol Clin (Paris)] 2007 May-Jun; Vol. 65 (3), pp. 257-64.
Publication Year :
2007

Abstract

In addition to the serological systematic screening tests, kits to measure the avidity of toxoplasma IgG antibodies are currently available. Since high-avidity IgG toxoplasma antibodies have been shown to exclude recent infection, IgG avidity determination is especially useful in ruling out acute infection having occurred in the 3-4 prior months of pregnancy. We therefore compared the efficacy of two toxoplasma IgG avidity ELISA kits: SFRI (SFRI Laboratoire) and VIDAS Toxo-IgG avidity kit (bioMérieux). The agreement of the results from the 2 commercial assays were analysed using 55 serum samples, in terms of global mother-child Toxoplasma results and outcome, specially with light of the results of Toxoplasma antenatal, postnatal assays and of clinical follow up of children.

Details

Language :
French
ISSN :
0003-3898
Volume :
65
Issue :
3
Database :
MEDLINE
Journal :
Annales de biologie clinique
Publication Type :
Academic Journal
Accession number :
17502297