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A two-way street: LSD1 regulates chromatin boundary formation in S. pombe and Drosophila.
- Source :
-
Molecular cell [Mol Cell] 2007 Apr 27; Vol. 26 (2), pp. 160-2. - Publication Year :
- 2007
-
Abstract
- Two recent studies in Molecular Cell (Lan et al., 2007; Rudolph et al., 2007) implicate histone demethylation by LSD1 in the regulation of boundaries between silenced and active chromatin domains in both fission yeast and flies, but by distinct mechanisms.
- Subjects :
- Animals
Euchromatin enzymology
Euchromatin genetics
Genes, Fungal
Genes, Insect
Heterochromatin enzymology
Heterochromatin genetics
Histones metabolism
Models, Biological
Schizosaccharomyces pombe Proteins genetics
Schizosaccharomyces pombe Proteins metabolism
Chromatin enzymology
Chromatin genetics
Drosophila Proteins genetics
Drosophila Proteins metabolism
Drosophila melanogaster enzymology
Drosophila melanogaster genetics
Oxidoreductases, N-Demethylating genetics
Oxidoreductases, N-Demethylating metabolism
Schizosaccharomyces enzymology
Schizosaccharomyces genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1097-2765
- Volume :
- 26
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Molecular cell
- Publication Type :
- Academic Journal
- Accession number :
- 17466618
- Full Text :
- https://doi.org/10.1016/j.molcel.2007.04.009