Back to Search
Start Over
Outcomes of HIV-infected children with tuberculosis who are started on antiretroviral therapy in Malawi.
- Source :
-
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease [Int J Tuberc Lung Dis] 2007 May; Vol. 11 (5), pp. 534-8. - Publication Year :
- 2007
-
Abstract
- Setting: Mzuzu Central Hospital, in the northern region of Malawi, which provides free antiretroviral therapy (ART) to human immunodeficiency virus (HIV) infected adults and children, including those with tuberculosis (TB).<br />Objectives: To compare outcomes in HIV-infected children who have been started on ART because of 1) active TB, 2) a past history of TB in the last 2 years and 3) a non-TB diagnosis.<br />Design: Retrospective data collection using ART patient master cards and ART patient registers.<br />Results: Between July 2004 and September 2006, 439 (11%) children of a total 3908 patients were started on ART. There were 29 with active TB, 56 with a past history of TB in the last 2 years and 354 with a non-TB diagnosis. The three groups were similar in nutritional indices and CD4-lymphocyte percentages. The 6-month probability of survival was 0.86 in the active TB group, 0.94 in the past history of TB group and 0.89 in the non-TB group. 12-month survival probability for the same groups was 0.86, 0.86 and 0.88, respectively.<br />Conclusion: HIV-infected children with active and previous TB who are started on ART have good outcomes that are similar to those of children started on ART due to a non-TB diagnosis.
- Subjects :
- Adolescent
Antitubercular Agents therapeutic use
Child
Child, Preschool
Female
Follow-Up Studies
HIV Infections mortality
Humans
Infant
Malawi
Male
Retrospective Studies
Survival Rate
Treatment Outcome
Tuberculosis drug therapy
Anti-HIV Agents therapeutic use
HIV Infections complications
HIV Infections drug therapy
Tuberculosis complications
Subjects
Details
- Language :
- English
- ISSN :
- 1027-3719
- Volume :
- 11
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
- Publication Type :
- Academic Journal
- Accession number :
- 17439677