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Poly(rA) binds poly(rG).poly(rC) to form a triple helix.

Authors :
Chastain M
Tinoco I Jr
Source :
Nucleic acids research [Nucleic Acids Res] 1992 Jan 25; Vol. 20 (2), pp. 315-8.
Publication Year :
1992

Abstract

Poly(rA) binds poly(rG).poly(rC) to form a triple helix. Evidence for this structure includes ultraviolet absorbance mixing curves and melting curves, and circular dichroism spectroscopy. The formation of the triple helix depends on the length of the poly(rC) strand. Triple helix forms when the average length is around 100 nucleotides but does not form when the average length is about 500 nucleotides.

Subjects

Subjects :
Circular Dichroism
Macromolecular Substances
Nucleic Acid Conformation
Poly A chemistry
Poly C chemistry
Poly G chemistry
Spectrophotometry
Temperature
Poly A metabolism
Poly C metabolism
Poly G metabolism

Details

Language :
English
ISSN :
0305-1048
Volume :
20
Issue :
2
Database :
MEDLINE
Journal :
Nucleic acids research
Publication Type :
Academic Journal
Accession number :
1741257
Full Text :
https://doi.org/10.1093/nar/20.2.315
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