Eosinophilic granuloma of the skin: response to intralesional corticosteroid injection.

Langerhans cell histiocytosis (LCH) is a histiocytic disorder in which the Langerhans cell is arrested in a premature, partially active state. The disease comprises a spectrum of disorders, the most benign of which is a single-system unifocal disease. Lesions in single-system LCH are typically limited to the bone. We report a case of a 66-year-old man with a single-system disease limited to the skin, who was successfully treated with intralesional triamcinolone. This minimally invasive treatment method warrants further studies of intralesional corticosteroid injection for skin lesions of LCH.