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Outcome assessments in children with cerebral palsy, part II: discriminatory ability of outcome tools.
- Source :
-
Developmental medicine and child neurology [Dev Med Child Neurol] 2007 Mar; Vol. 49 (3), pp. 181-6. - Publication Year :
- 2007
-
Abstract
- Discriminatory ability of several pediatric outcome tools was assessed relative to Gross Motor Function Classification System (GMFCS) level in patients with cerebral palsy. Five hundred and sixty-two patients (400 with diplegia, 162 with hemiplegia; 339 males, 223 females; age range 4-18y, mean 11y 1mo [SD 3y 7mo]), classified as GMFCS Levels I to III, participated in this prospective multicenter, cross-sectional study. All tools were completed by parents and participants when appropriate. Effect size indices (ESIs) for parametric variables and odds ratios for non-parametric data quantified the magnitude of differences across GMFCS levels. Binary logistic regression models determined discrimination, and receiver operating characteristic curves addressed sensitivity and specificity. Between Levels I and II, the most discriminatory tools were Gross Motor Function Measure (GMFM-66), velocity, and WeeFIM Mobility. Between Levels II and III, the most discriminatory tools were GMFM Dimension E, Pediatric Functional Independence Measure (WeeFIM) Self-Care and Mobility, cadence, and Gillette Functional Assessment Questionnaire Question 1. Large ESIs were noted for Parent and Child reports of Pediatric Outcomes Data Collection Instrument (PODCI) Sports & Physical Function, Parent report of PODCI Global Function, GMFM Dimension E, and GMFM-66 across all GMFCS level comparisons. The least discriminatory tools were the Quality of Life and cognition measures; however, these are important in comprehensive assessments of treatment effects.
- Subjects :
- Activities of Daily Living
Adolescent
Analysis of Variance
Cerebral Palsy diagnosis
Cerebral Palsy therapy
Child
Child, Preschool
Cross-Sectional Studies
Female
Humans
Male
Motor Skills Disorders complications
Motor Skills Disorders diagnosis
Orthopedics methods
Prospective Studies
Reproducibility of Results
Severity of Illness Index
Cerebral Palsy complications
Disability Evaluation
Motor Skills classification
Motor Skills Disorders classification
Outcome Assessment, Health Care methods
Subjects
Details
- Language :
- English
- ISSN :
- 0012-1622
- Volume :
- 49
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Developmental medicine and child neurology
- Publication Type :
- Academic Journal
- Accession number :
- 17355473
- Full Text :
- https://doi.org/10.1111/j.1469-8749.2007.00181.x