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Performance of rapid HIV testing using Determine HIV-1/2 for the diagnosis of HIV infection during pregnancy in Tijuana, Baja California, Mexico.
- Source :
-
International journal of STD & AIDS [Int J STD AIDS] 2007 Feb; Vol. 18 (2), pp. 101-4. - Publication Year :
- 2007
-
Abstract
- The aim of this study was to evaluate the performance of the rapid antibody test Determine HIV-1/2, in pregnant women at Tijuana General Hospital. Pregnant women seeking prenatal care or admitted in labour had blood drawn for a rapid HIV test (Determine HIV-1/2), enzyme immunoassay (EIA) and Western blot. Between March and November 2003, 1068 women in labour and 1529 women in prenatal care were enrolled. The sensitivity, specificity, positive and negative predictive values were 100%, 99.8%, 77% and 100%, respectively. For women in labour, the mean time between blood collection and rapid test results was 92 minutes (range: 20-205 minutes) compared with 41 hours (range 24-120 hours) for HIV EIA (P = 0.012). All HIV-exposed infants received oral zidovudine. These findings indicate that the rapid test Determine HIV-1/2 has a high sensitivity and specificity in pregnant women. Rapid HIV testing greatly diminishes the time to diagnosis and enables prompt intervention with antiretrovirals at delivery.
- Subjects :
- Female
HIV Infections transmission
HIV Infections virology
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases virology
Infectious Disease Transmission, Vertical
Mexico
Predictive Value of Tests
Pregnancy
Pregnancy Complications, Infectious virology
Sensitivity and Specificity
Time Factors
AIDS Serodiagnosis
HIV Antibodies blood
HIV Infections diagnosis
HIV-1 immunology
HIV-2 immunology
Infant, Premature, Diseases diagnosis
Pregnancy Complications, Infectious diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 0956-4624
- Volume :
- 18
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- International journal of STD & AIDS
- Publication Type :
- Academic Journal
- Accession number :
- 17331281
- Full Text :
- https://doi.org/10.1258/095646207779949655