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Preoperative cellulose porous beads for therapeutic embolization of meningioma: provocation test and technical considerations.
- Source :
-
Neuroradiology [Neuroradiology] 2007 May; Vol. 49 (5), pp. 437-43. Date of Electronic Publication: 2007 Feb 22. - Publication Year :
- 2007
-
Abstract
- Introduction: Cellulose porous beads (CPBs) are exceptionally uniform in size and nonabsorbable and they provide highly effective tumor devascularization. The risk of cranial nerve palsy must not be overlooked when embolization with CPBs is considered in meningioma patients. We attempted to identify patients at risk of cranial nerve palsy after meningioma embolization.<br />Methods: Prior to preoperative superselective embolization with 200 mum diameter CPBs, 141 patients with meningioma underwent provocation test with lidocaine and amytal. They were divided into two groups on the basis of whether they were or were not considered eligible for embolization. We evaluated the differences between the two groups with respect to tumor anatomy, angiographic findings, and clinical presentation and recorded complications associated with the embolization of the meningioma.<br />Results: Of the 141 patients, 128 underwent CPB embolization (group 2); 13 were not embolized because their provocation test results were positive (group 1, n = 11) or because they showed vasospasm (n = 2). Group 1 patients had meningioma in the cavernous sinus or petroclival region. Characteristically, the feeders were of middle meningeal artery origin and exhibited a posteromedial course toward the petrous apex or cavernous sinus. In group 2 patients the middle meningeal artery was the feeder, but it lacked branches coursing posteromedially. Three of these patients experienced complications which included intratumoral hemorrhage (n = 2) and post-embolization hearing disturbance (n = 1).<br />Conclusion: Patients with meningioma whose tumor-feeding arteries run posteromedially toward the petrous apex or cavernous sinus are at increased risk of post-embolization cranial nerve palsy. Appropriate protocols, including lidocaine and amytal provocation tests, may reduce the risk of complications after CPB embolization of the external carotid territory in this group of patients.
- Subjects :
- Adult
Aged
Female
Humans
Male
Meningeal Neoplasms diagnosis
Meningeal Neoplasms surgery
Meningioma diagnosis
Meningioma surgery
Middle Aged
Particle Size
Risk Factors
Treatment Outcome
Angiography, Digital Subtraction
Cellulose
Cerebral Angiography
Embolization, Therapeutic methods
Meningeal Neoplasms blood supply
Meningioma blood supply
Microspheres
Neoadjuvant Therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0028-3940
- Volume :
- 49
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Neuroradiology
- Publication Type :
- Academic Journal
- Accession number :
- 17318600
- Full Text :
- https://doi.org/10.1007/s00234-007-0218-0