New C-3' hydroxamate-substituted and more lipophilic cyclic hydroxamate cephalosporin derivatives as a potential new generation of selective antimicrobial agents.

Subjects

Subjects :

Animals
Anti-Bacterial Agents chemical synthesis
Anti-Bacterial Agents chemistry
Cephalosporins chemical synthesis
Cephalosporins chemistry
Chlorocebus aethiops
Cyclization
Hydroxamic Acids chemistry
Microbial Sensitivity Tests
Molecular Conformation
Stereoisomerism
Structure-Activity Relationship
Vero Cells drug effects
Anti-Bacterial Agents pharmacology
Bacillus subtilis drug effects
Cephalosporins pharmacology
Micrococcus luteus drug effects
Mycobacterium tuberculosis drug effects
Staphylococcus aureus drug effects

Details

Language :

English

ISSN :

1477-0520

Volume :

4

Issue :

22

Database :

MEDLINE

Journal :

Organic & biomolecular chemistry

Publication Type :

Academic Journal

Accession number :

17312974

Full Text :

https://doi.org/10.1039/b612475e