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Diagnosis and treatment of ocular coccidioidomycosis in a female captive chimpanzee (Pan troglodytes): a case study.
- Source :
-
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2007 Sep; Vol. 1111, pp. 404-10. Date of Electronic Publication: 2007 Feb 15. - Publication Year :
- 2007
-
Abstract
- We report here the first documented case of ocular coccidioidomycosis in a chimpanzee (Pan troglodytes). In 1996, a 12-year-old female chimpanzee was undergoing treatment with an experimental triazole, BayR3783, for coccidioidomycosis when she was diagnosed with severe conjunctivitis in the right eye. Subsequent development of a coccidioidal granuloma of the ventral conjunctiva and anterior uvea was noted over the next several months, distorting the lens, iris, pupil, and sclera and progressing to uveitis. Treatment with BayR3783 and subconjunctival injections of triamcinolone were successful in reducing the ocular mass, but extensive damage was done to the lens and cornea. This case study provides an interesting comparison to ocular coccidioidomycosis cases observed in both humans and canines.
- Subjects :
- Animals
Coccidioides metabolism
Coccidioidomycosis microbiology
Coccidioidomycosis veterinary
Conjunctivitis diagnosis
Conjunctivitis microbiology
Conjunctivitis therapy
Conjunctivitis veterinary
Female
Ketoconazole therapeutic use
Models, Anatomic
Pan troglodytes
Uveitis microbiology
Uveitis veterinary
Coccidioidomycosis diagnosis
Coccidioidomycosis therapy
Eye microbiology
Uveitis diagnosis
Uveitis therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0077-8923
- Volume :
- 1111
- Database :
- MEDLINE
- Journal :
- Annals of the New York Academy of Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 17303834
- Full Text :
- https://doi.org/10.1196/annals.1406.018