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Three-dimensional relationship between high-order root-mean-square wavefront error, pupil diameter, and aging.
- Source :
-
Journal of the Optical Society of America. A, Optics, image science, and vision [J Opt Soc Am A Opt Image Sci Vis] 2007 Mar; Vol. 24 (3), pp. 578-87. - Publication Year :
- 2007
-
Abstract
- We report root-mean-square (RMS) wavefront error (WFE) for individual aberrations and cumulative high-order (HO) RMS WFE for the normal human eye as a function of age by decade and pupil diameter in 1 mm steps from 3 to 7 mm and determine the relationship among HO RMS WFE, mean age for each decade of life, and luminance for physiologic pupil diameters. Subjects included 146 healthy individuals from 20 to 80 years of age. Ocular aberration was measured on the preferred eye of each subject (for a total of 146 eyes through dilated pupils; computed for 3, 4, 5, 6, and 7 mm pupils; and described with a tenth-radial-order normalized Zernike expansion. We found that HO RMS WFE increases faster with increasing pupil diameter for any given age and pupil diameter than it does with increasing age alone. A planar function accounts for 99% of the variance in the 3-D space defined by mean log HO RMS WFE, mean age for each decade of life, and pupil diameter. When physiologic pupil diameters are used to estimate HO RMS WFE as a function of luminance and age, at low luminance (9 cd/m2) HO RMS WFE decreases with increasing age. This normative data set details (1) the 3-D relationship between HO RMS WFE and age for fixed pupil diameters and (2) the 3-D relationship among HO RMS WFE, age, and luminance for physiologic pupil diameters.
- Subjects :
- Adult
Aged
Aged, 80 and over
Computer Simulation
Female
Humans
Male
Middle Aged
Reproducibility of Results
Rotation
Sensitivity and Specificity
Aging physiology
Algorithms
Corneal Topography methods
Image Interpretation, Computer-Assisted methods
Imaging, Three-Dimensional methods
Iris physiology
Models, Biological
Subjects
Details
- Language :
- English
- ISSN :
- 1084-7529
- Volume :
- 24
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of the Optical Society of America. A, Optics, image science, and vision
- Publication Type :
- Academic Journal
- Accession number :
- 17301847
- Full Text :
- https://doi.org/10.1364/josaa.24.000578