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[Proliferation of myofibroblast in periodental tension side during orthodontic tooth movement of beagle dogs].

[Proliferation of myofibroblast in periodental tension side during orthodontic tooth movement of beagle dogs].

Authors :
Meng Y
Bai D
Han XL
Liu M
Huang L
Bao LN
Source :
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition [Sichuan Da Xue Xue Bao Yi Xue Ban] 2007 Jan; Vol. 38 (1), pp. 123-5, 141.
Publication Year :
2007

Abstract

Objective: To examine the proliferation of myofibroblast in periodental tension side of beagle dog during experimental tooth movement in orthodontics.<br />Methods: By the fixed orthodontic appliance, the five beagles were treated with 100 g forces that moved medially the maxillary first premolar, and the treatment lasted for four weeks. Using transmission electron microscope and immunohistochemistry, the proliferation of myofibroblast and expression of alpha-smooth muscle actin (alpha-SMA) were evaluated at week 1, 2, 3, 4 or 8 respectively after the orthodontic treatment.<br />Results: During the total of four weeks, the expression of a-SMA increased in week 1 and reached the maximum in week 2; in week 4, the expression of alpha-SMA went back to normal level. Transmission electron microscopy showed that the myofibroblast contained the dense body appearing in cytoplasm.<br />Conclusion: The myofibroblast exists in periodontium and is concerned with the orthodontic tooth movement.

Details

Language :
Chinese
ISSN :
1672-173X
Volume :
38
Issue :
1
Database :
MEDLINE
Journal :
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
Publication Type :
Academic Journal
Accession number :
17294745