Back to Search
Start Over
Fetal heart rate accelerations and the risk of cerebral lesions and poor neurodevelopmental outcome in very low birthweight neonates.
- Source :
-
American journal of perinatology [Am J Perinatol] 2007 Feb; Vol. 24 (2), pp. 83-8. Date of Electronic Publication: 2007 Jan 29. - Publication Year :
- 2007
-
Abstract
- The risk of intraventricular hemorrhage and periventricular leukomalacia correlates with fetal brain immaturity. Given that the appearance of fetal heart rate (FHR) accelerations is associated with brain maturation, we tested the hypothesis that neonatal cerebral lesions and developmental delay in very low birthweight newborns are associated with absent reactivity of the FHR tracing prior to delivery. We analyzed the FHR tracing of 97 fetuses with birthweight < 1200 g who underwent head ultrasound at day 3 and Bayley Scales of Infant Development testing at age 1 year. We used multivariate analysis to adjust for confounding variables. We found that the absence of two FHR accelerations of 10 beats per minute (bpm) for 10 seconds twice in a 20-minute window 1 hour before delivery was associated with intraventricular hemorrhage and/or periventricular leukomalacia ( P < 0.01) and a significant risk for mental and psychomotor delays by Bayley testing ( P < 0.001). The absence of accelerations of 15 bpm for 15 seconds was not associated with these abnormalities. The absence of FHR accelerations before delivery suggests a greater risk for cerebral injury and developmental delay in the very premature neonate.
- Subjects :
- Adult
Developmental Disabilities physiopathology
Female
Humans
Infant, Newborn
Multivariate Analysis
Obstetric Labor, Premature epidemiology
Pre-Eclampsia epidemiology
Pregnancy
Retrospective Studies
Risk Assessment
Cerebral Hemorrhage physiopathology
Heart Rate, Fetal physiology
Infant, Very Low Birth Weight physiology
Leukomalacia, Periventricular physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 0735-1631
- Volume :
- 24
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- American journal of perinatology
- Publication Type :
- Academic Journal
- Accession number :
- 17260327
- Full Text :
- https://doi.org/10.1055/s-2006-958161