Back to Search
Start Over
Stille/Diels-Alder reaction sequences: diversity-oriented access to novel steroids.
- Source :
-
Organic letters [Org Lett] 2007 Feb 01; Vol. 9 (3), pp. 517-20. - Publication Year :
- 2007
-
Abstract
- [reaction: see text] An efficient, diversity-oriented approach to novel steroid analogues possessing a C-5beta configuration begins with the Stille cross-coupling of enantiomerically pure cycloalkenylstannane trans-2 and enol triflate 3. The resulting diene trans-4 engages in Diels-Alder cycloaddition reactions with a range of dienophiles to give, after removal of protecting groups, biologically interesting 6,7-disubstituted steroid analogues.
Details
- Language :
- English
- ISSN :
- 1523-7060
- Volume :
- 9
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 17249801
- Full Text :
- https://doi.org/10.1021/ol062878m