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Chronic myelomonocytic leukaemia (an analysis of fourteen consecutive cases).
- Source :
-
The Journal of the Association of Physicians of India [J Assoc Physicians India] 1991 May; Vol. 39 (5), pp. 390-3. - Publication Year :
- 1991
-
Abstract
- Fourteen consecutive cases of chronic myelomonocytic leukaemia aged 6 to 73 (mean 40.5) years were reviewed to define the natural history of the disease and the risk of acute transformation. The common presenting features included anaemia, fever, purpura, and bleeding tendencies. Abnormal karyotypes were seen in 4 of 6 patients subjected to cytogenetic analysis. Low dose cytosine arabinoside achieved complete remission in two and partial remission in one, of the four patients treated with this modality. The mean survival was 5.6 (range 2-12) months and two patients) evolved to acute myeloid leukaemia. The long term survival with the present form of therapy in chronic myelomonocytic leukaemia is poor.
- Subjects :
- Adolescent
Adult
Aged
Antineoplastic Agents therapeutic use
Biopsy, Needle
Blood Cell Count
Bone Marrow pathology
Child
Female
Fetal Hemoglobin analysis
Humans
India
Leukemia, Myelomonocytic, Chronic drug therapy
Leukemia, Myelomonocytic, Chronic mortality
Male
Middle Aged
Survival Rate
Leukemia, Myelomonocytic, Chronic diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 0004-5772
- Volume :
- 39
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- The Journal of the Association of Physicians of India
- Publication Type :
- Academic Journal
- Accession number :
- 1720434