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Black tea ameliorates aflatoxin-induced lipid peroxidation in the kidney of mice.
- Source :
-
Acta poloniae pharmaceutica [Acta Pol Pharm] 2006 Jul-Aug; Vol. 63 (4), pp. 307-10. - Publication Year :
- 2006
-
Abstract
- Oral administration of 25 and 50 mg of aflatoxin in 0.2 mL olive oil/animal/day for 30 days caused dose-dependent and significantly higher lipid peroxidation in the kidney of aflatoxin-treated mice than in the controls. The levels of non-enzymatic antioxidant such as glutathione as well as the enzymatic antioxidants such as superoxide dismutase, glutathione peroxidase and catalase were significantly lower in the kidney of aflatoxin-treated mice than in the controls. Black tea extract (2%) treatment significantly ameliorates aflatoxin-induced lipid peroxidation, which could be due to higher enzymatic and non-enzymatic antioxidants in the kidney of mice as compared with that given aflatoxin alone. These findings suggest that black tea extract treatment significantly ameliorates aflatoxin-induced lipid peroxidation in the kidney of mice.
Details
- Language :
- English
- ISSN :
- 0001-6837
- Volume :
- 63
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Acta poloniae pharmaceutica
- Publication Type :
- Academic Journal
- Accession number :
- 17203869