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Markers of human papillomavirus infection and their correlation with cervical dysplasia in human immunodeficiency virus-positive women.
- Source :
-
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2007 Jan; Vol. 13 (1), pp. 94-7. - Publication Year :
- 2007
-
Abstract
- Human papillomavirus (HPV) genotypes and HPV DNA load were analysed in cervical smears from 76 human immunodeficiency virus (HIV)-positive and 54 HIV-negative women. The prevalence of genotypes was similar for all women, with the exception of HPV62, which was over-represented in HIV-positive samples. HIV-positive women showed a higher prevalence of multiple genotypes that correlated neither with CD4(+) T-cell counts nor with cervical dysplasia. No significant differences were observed in terms of total or single-type HPV DNA load. The HPV DNA load in both HIV-positive and HIV-negative women was significantly higher in squamous intra-epithelial lesions than in negative Pap smears.
- Subjects :
- Adult
DNA, Viral genetics
Female
Genetic Markers genetics
Humans
Middle Aged
Papillomaviridae classification
Polymerase Chain Reaction
Species Specificity
HIV
HIV Infections complications
Neoplasms, Squamous Cell complications
Neoplasms, Squamous Cell virology
Papillomaviridae genetics
Papillomavirus Infections complications
Papillomavirus Infections virology
Uterine Cervical Dysplasia complications
Uterine Cervical Dysplasia virology
Subjects
Details
- Language :
- English
- ISSN :
- 1198-743X
- Volume :
- 13
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 17184295
- Full Text :
- https://doi.org/10.1111/j.1469-0691.2006.01568.x