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Dietary microbial levan enhances cellular non-specific immunity and survival of common carp (Cyprinus carpio) juveniles.
- Source :
-
Fish & shellfish immunology [Fish Shellfish Immunol] 2007 May; Vol. 22 (5), pp. 477-86. Date of Electronic Publication: 2006 Jun 15. - Publication Year :
- 2007
-
Abstract
- A preliminary study with a 75days feeding trial was conducted to study the immunomodulatory effect of microbial levan on Cyprinus carpio juveniles. Five purified isonitrogenous and isocaloric diets with graded levels of levan, namely (T(1)) 0.1% levan, (T(2)) 0.2% levan, (T(3)) 0.5% levan, (T(4)) 1.0% levan, and a control group without levan were fed to five groups of fishes in triplicate. The total erythrocyte count and haemoglobin content was significantly (p<0.05) enhanced in the T(3) group, though the total leucocyte counts, total protein and A/G ratio did not show any significant difference (p>0.05) when compared with the control group. The respiratory burst activity (NBT) of blood phagocytes and lysozyme activity was also highest in T(3) group. The relative survival percentage after challenge with Aeromonas hydrophila was highest (100%) in the T(3) group followed by 83.33% and 66.67% in the T(2) and T(4) groups, respectively. This suggests that microbial levan at 0.5% can be used as a dietary immunostimulant for C. carpio juveniles. This is the first report on microbial levan having an immunomodulatory effect on C. carpio.
- Subjects :
- Adjuvants, Immunologic administration & dosage
Aeromonas hydrophila immunology
Aeromonas hydrophila pathogenicity
Animal Feed analysis
Animals
Erythrocytes drug effects
Fish Diseases immunology
Fructans administration & dosage
Fructans chemistry
Gram-Negative Bacterial Infections immunology
Gram-Negative Bacterial Infections veterinary
Hemoglobins analysis
Muramidase blood
Muramidase drug effects
Phagocytes drug effects
Phagocytes immunology
Random Allocation
Respiratory Burst drug effects
Survival Analysis
Time Factors
Adjuvants, Immunologic pharmacology
Carps immunology
Diet veterinary
Fructans pharmacology
Immunity, Innate drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 1050-4648
- Volume :
- 22
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Fish & shellfish immunology
- Publication Type :
- Academic Journal
- Accession number :
- 17158064
- Full Text :
- https://doi.org/10.1016/j.fsi.2006.06.005