Sex-based centers of care: a look to the future.

Although sex-based centers of care have played a critical historic role in improving the health of their constituents and drawing attention to the different health care needs of men and women, it is time to challenge them to do an even better job. There are now overwhelming data showing that men and women are profoundly different at the molecular and cellular level in virtually all aspects of musculoskeletal health and disease, but the clinical implications of these differences have generally been unexplored. Sex-based health centers of care can play a critical role in exploring these difference, and, in doing so, reduce disability and enhance quality of life in our growing population of senior men and women.