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Treatment with flunitrazepam of continuous spikes and waves during slow wave sleep (CSWS) in children.
- Source :
-
Seizure [Seizure] 2007 Mar; Vol. 16 (2), pp. 190-2. Date of Electronic Publication: 2006 Nov 30. - Publication Year :
- 2007
-
Abstract
- We describe our treatment of two boys with continuous spikes and waves during slow wave sleep (CSWS). One of the boys was suffering from non-convulsive status epilepticus and the other from conscious disturbance with automatism. Their ictal EEG readings showed continuous diffuse spike and wave complexes, which were considered to show electrical status. The boys were diagnosed as having CSWS, and were later diagnosed with Landau-Kleffner syndrome (LKS). EEG readings returned to normal on intravenous injection of flunitazepam (FZP) at a dose of 0.02 mg/kg, suggesting that FZP is an effective treatment for CSWS.
- Subjects :
- Child
Humans
Landau-Kleffner Syndrome drug therapy
Male
Sleep physiology
Status Epilepticus drug therapy
Status Epilepticus physiopathology
Anticonvulsants therapeutic use
Electroencephalography drug effects
Epilepsy pathology
Flunitrazepam therapeutic use
Landau-Kleffner Syndrome diagnosis
Sleep drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 1059-1311
- Volume :
- 16
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Seizure
- Publication Type :
- Academic Journal
- Accession number :
- 17140816
- Full Text :
- https://doi.org/10.1016/j.seizure.2006.10.013