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An immunochemical approach to model and long-term suppression of depressive and anxiety behavior.
- Source :
-
The Spanish journal of psychology [Span J Psychol] 2006 Nov; Vol. 9 (2), pp. 219-27. - Publication Year :
- 2006
-
Abstract
- The inhibitor of monoaminooxydase isatin and the ligand of B-receptors cholecystokinin-4 play a significant role in the suppression and induction of depressive and anxiety states. We induced the formation of auto-antibodies to these compounds against their conjugates with antigen-carrier by immunization of white rats. The result was long-term (more than 2 months) stimulation of depressive and anxiety behavior after immunization to isatin and, in contrast, the suppression of such behavior after immunization to cholecystokinin. The perspective of immunochemical approach to long-term correction of behavior is discussed.
Details
- Language :
- English
- ISSN :
- 1138-7416
- Volume :
- 9
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The Spanish journal of psychology
- Publication Type :
- Academic Journal
- Accession number :
- 17120701
- Full Text :
- https://doi.org/10.1017/s1138741600006119