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Acute myelogenous leukemia mimicking a hemolysis, elevated liver enzymes, and low platelets syndrome during pregnancy: case report and review of the literature.
- Source :
-
American journal of perinatology [Am J Perinatol] 2007 Jan; Vol. 24 (1), pp. 1-4. Date of Electronic Publication: 2006 Nov 08. - Publication Year :
- 2007
-
Abstract
- Acute leukemia is a rare malignancy of pregnancy. When it develops, there are many complications to consider and management becomes exceedingly difficult. We report a case of acute myelogenous leukemia presenting as preeclampsia and fetal demise at 36 weeks of gestation. A 30-year-old multigravida presented with intrauterine fetal demise at 36 weeks' gestation, hypertension, and thrombocytopenia. The patient received platelet and packed red blood cell transfusion, with concurrent prophylactic magnesium sulfate and dexamethasone treatment. Following labor induction, the patient delivered a nonviable female fetus and suffered a stroke postpartum. Peripheral smear and flow cytometry revealed the patient had acute myeloid leukemia with prominent monocytic differentiation. The patient expired on postpartum day six. Acute leukemia during the pregnancy is associated with an unfavorable outcome.
- Subjects :
- Adult
Diagnosis, Differential
Fatal Outcome
Female
Fetal Death
Hemolysis
Humans
Leukemia, Monocytic, Acute blood
Leukemia, Monocytic, Acute complications
Leukemia, Monocytic, Acute pathology
Liver enzymology
Platelet Transfusion
Pregnancy
Pregnancy Complications, Neoplastic blood
Pregnancy Complications, Neoplastic pathology
Pregnancy Trimester, Third
Thrombocytopenia blood
Leukemia, Monocytic, Acute diagnosis
Pregnancy Complications, Neoplastic diagnosis
Prenatal Diagnosis
Thrombocytopenia etiology
Subjects
Details
- Language :
- English
- ISSN :
- 0735-1631
- Volume :
- 24
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- American journal of perinatology
- Publication Type :
- Academic Journal
- Accession number :
- 17094046
- Full Text :
- https://doi.org/10.1055/s-2006-954955