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[Atherosclerosis and infection?].
- Source :
-
Vnitrni lekarstvi [Vnitr Lek] 2006 Sep; Vol. 52 (9), pp. 823-6. - Publication Year :
- 2006
-
Abstract
- Atherosclerosis is guided by chronicle inflammation process. In the last decades of the 20th century, studies considering infection another possible risk factor of atherosclerosis development were written. Helicobacter pylori, Porphyromas gingivalis, some viruses but most frequently Chlamydia pneumonie are infection agens mentioned in these studies. Some of them emphasize also combined infections caused by more pathogenic factors having influence on vascular inflammation. Serological, epidemiological, histological and imunological studies show the pathogenic influence of acute or chronic infections. Many studies selected makrolid antibiotics as treatment in patients with ischaemic heart disease. However, existing experience with antibiotics did not bring clear results. These studies have mentioned the fact antibiotics have not been indicated as treatment in patients with acute or chronic vascular system infliction by atherosclerosis. Since the experimental and clinical research of influence of inflammations on the development of atherosclerosis moved forward a lot, no exact evidence of this complicated pathogenic mechanism was given. It will obviously take some time to confirm whether the relation between infections and artherosclerosis is causal, i.e. initiating the pathogenic process, accelerating it or keeping it alive.
- Subjects :
- Anti-Bacterial Agents therapeutic use
Atherosclerosis drug therapy
Atherosclerosis immunology
Atherosclerosis pathology
Bacterial Infections immunology
Chlamydophila Infections complications
Chlamydophila pneumoniae
Humans
Immunity
Inflammation
Risk Factors
Virus Diseases complications
Virus Diseases immunology
Atherosclerosis microbiology
Bacterial Infections complications
Subjects
Details
- Language :
- Czech
- ISSN :
- 0042-773X
- Volume :
- 52
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Vnitrni lekarstvi
- Publication Type :
- Academic Journal
- Accession number :
- 17091609