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[Discriminant analysis of quantification theory on prognostic factors of chemotherapeutic effects on advanced testicular cancer. East Japan Testicular Tumor Study Group].
- Source :
-
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology [Nihon Hinyokika Gakkai Zasshi] 1990 Dec; Vol. 81 (12), pp. 1825-9. - Publication Year :
- 1990
-
Abstract
- Prognostic factors of chemotherapy against advanced testicular cancer were analysed in 33 cases studied by East Japan Testicular Tumor Study Group. In this study a discriminant analysis of quantification theory (a multivariate analysis) was adapted, taking 7 factors as comparative variables. The significant factors for complete tumor response were clinical stage, histology, and tumor markers (HCG-beta, AFP). Prognostic score was calculated in each case by quantification theory, which correctly discriminated the group with CR from that without CR, at a probability of 90.1%. The results of our study indicate that the outcome of chemotherapy on advanced testicular cancer may be predicted with probability, by patients' status and adopted treatment. It may enable one to make an adequate treatment schedule for each patient.
- Subjects :
- Bleomycin administration & dosage
Cisplatin administration & dosage
Discriminant Analysis
Etoposide administration & dosage
Humans
Male
Multivariate Analysis
Prognosis
Remission Induction
Vinblastine administration & dosage
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Testicular Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0021-5287
- Volume :
- 81
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Nihon Hinyokika Gakkai zasshi. The japanese journal of urology
- Publication Type :
- Academic Journal
- Accession number :
- 1705588
- Full Text :
- https://doi.org/10.5980/jpnjurol1989.81.1825