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MassTag polymerase-chain-reaction detection of respiratory pathogens, including a new rhinovirus genotype, that caused influenza-like illness in New York State during 2004-2005.
- Source :
-
The Journal of infectious diseases [J Infect Dis] 2006 Nov 15; Vol. 194 (10), pp. 1398-402. Date of Electronic Publication: 2006 Oct 06. - Publication Year :
- 2006
-
Abstract
- In New York State during winter 2004, there was a high incidence of influenza-like illness that tested negative both for influenza virus, by molecular methods, and for other respiratory viruses, by virus culture. Concern that a novel pathogen might be implicated led us to implement a new multiplex diagnostic tool. MassTag polymerase chain reaction resolved 26 of 79 previously negative samples, revealing the presence of rhinoviruses in a large proportion of samples, half of which belonged to a previously uncharacterized genetic clade. In some instances, knowledge of the detected viral and/or bacterial (co)infection could have altered clinical management.
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Bacteria classification
Bacteria genetics
Child
Child, Preschool
Humans
Infant
Middle Aged
Molecular Epidemiology
Molecular Sequence Data
New York epidemiology
Phylogeny
Picornaviridae Infections epidemiology
Picornaviridae Infections virology
Respiratory Tract Infections epidemiology
Rhinovirus classification
Rhinovirus genetics
Sequence Analysis, DNA
Viral Proteins genetics
Viruses classification
Viruses genetics
Bacteria isolation & purification
Polymerase Chain Reaction methods
Respiratory Tract Infections microbiology
Respiratory Tract Infections virology
Rhinovirus isolation & purification
Viruses isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 0022-1899
- Volume :
- 194
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- The Journal of infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 17054069
- Full Text :
- https://doi.org/10.1086/508551