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[Campylobacter jejuni and cytomegalovirus (CMV) infections in patients with the Guillain-Barre syndrome].

Authors :
Orlikowski D
Quijano-Roy S
Sivadon-Tardy V
Raphael JC
Gaillard JL
Source :
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie [Arch Pediatr] 2006 Dec; Vol. 13 (12), pp. 1561-5. Date of Electronic Publication: 2006 Oct 09.
Publication Year :
2006

Abstract

Guillain-Barre syndrome (GBS) is a rare disease triggered by postinfectious mechanisms. The disease concerns all ages, and is widely distributed around the world. The principal risks are respiratory failure, especially during the initial phase of the disease, and persisting deficit at long term. Among the infectious known agents, Campylobacter jejuni and CMV represent more than 40% of GBS causes. The clinical presentation, and the long-term prognosis of GBS related to these two etiologies are different. The physiopathological mechanisms of the nervous attack are probably also different. There is no proof, at this time, that anti-infectious treatment can improve the prognosis. The treatment is based on the early use of immunomodulatory treatments like intravenous immunoglobulins or plasma exchanges.

Details

Language :
French
ISSN :
0929-693X
Volume :
13
Issue :
12
Database :
MEDLINE
Journal :
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
Publication Type :
Academic Journal
Accession number :
17030119
Full Text :
https://doi.org/10.1016/j.arcped.2006.09.002