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Novel nucleotide triphosphates as potent P2Y2 agonists.
- Source :
-
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2007 Jan 15; Vol. 17 (2), pp. 562-5. Date of Electronic Publication: 2006 Sep 29. - Publication Year :
- 2007
-
Abstract
- The synthesis and P2Y2 activities of a novel series of nucleoside triphosphates are described. Many of these compounds were potent agonists of the P2Y2 receptor.
- Subjects :
- Cell Line, Tumor
DNA, Complementary biosynthesis
DNA, Complementary genetics
Humans
Indicators and Reagents
Magnetic Resonance Spectroscopy
Receptors, Purinergic P2Y2
Reverse Transcriptase Polymerase Chain Reaction
Structure-Activity Relationship
Uridine Triphosphate pharmacology
Nucleotides chemical synthesis
Nucleotides pharmacology
Purinergic P2 Receptor Agonists
Subjects
Details
- Language :
- English
- ISSN :
- 0960-894X
- Volume :
- 17
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Bioorganic & medicinal chemistry letters
- Publication Type :
- Academic Journal
- Accession number :
- 17011188
- Full Text :
- https://doi.org/10.1016/j.bmcl.2006.09.017