Back to Search
Start Over
Borrelia burgdorferi complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes is expressed in humans and induces antibody responses restricted to nondenatured structural determinants.
- Source :
-
Infection and immunity [Infect Immun] 2006 Dec; Vol. 74 (12), pp. 7024-8. Date of Electronic Publication: 2006 Sep 25. - Publication Year :
- 2006
-
Abstract
- Borrelia burgdorferi complement regulator-acquiring surface protein 1 (CRASP-1), the dominant factor H and FHL-1-binding protein of the Lyme disease spirochete B. burgdorferi, is implicated in pathogen persistence and was recently reported to be nonimmunogenic in humans. Here we show that serum samples from Lyme disease patients contain antibodies with exclusive specificity for nondenatured structural determinants of CRASP-1.
Details
- Language :
- English
- ISSN :
- 0019-9567
- Volume :
- 74
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Infection and immunity
- Publication Type :
- Academic Journal
- Accession number :
- 17000728
- Full Text :
- https://doi.org/10.1128/IAI.01028-06