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Complications in mammalian microRNA target prediction.

Authors :
Smalheiser NR
Torvik VI
Source :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2006; Vol. 342, pp. 115-27.
Publication Year :
2006

Abstract

In this chapter, we review evidence that at least three different types of microRNA (miRNA)-messenger RNA (mRNA) target interactions exist in mammals: short seeds, long seeds, and "perfect" hits (allowing G:U matches). Because new types of miRNAs are still being discovered, this list may not yet be complete.

Subjects

Subjects :
3' Untranslated Regions
Animals
Databases, Genetic
Expressed Sequence Tags
Long Interspersed Nucleotide Elements
Mammals classification
MicroRNAs chemistry
RNA Interference
RNA, Messenger chemistry
RNA, Messenger genetics
RNA, Messenger metabolism
Software
Mammals genetics
Mammals metabolism
MicroRNAs genetics
MicroRNAs metabolism

Details

Language :
English
ISSN :
1064-3745
Volume :
342
Database :
MEDLINE
Journal :
Methods in molecular biology (Clifton, N.J.)
Publication Type :
Academic Journal
Accession number :
16957371
Full Text :
https://doi.org/10.1385/1-59745-123-1:115
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Authors Abstract Subjects Details