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Adjunctive pharmacologic use in carotid endarterectomy: a review.
- Source :
-
Vascular [Vascular] 2006 Mar-Apr; Vol. 14 (2), pp. 93-102. - Publication Year :
- 2006
-
Abstract
- Although carotid endarterectomy (CEA) is now widely accepted as the surgical therapy for carotid stenosis, the role of and indications and evidence for many pharmacologic agents that are used adjunctively in the perioperative setting have not been conclusively established. Aspirin (acetylsalicylic acid) is the pharmaceutical agent that has been studied most extensively in conjunction with CEA; other than aspirin and dextran, the use of many agents before, during, and after CEA has not been standardized. Prospective randomized trials are still needed to demonstrate efficacy, predict outcome, and determine the optimal use of these medications in their adjunctive use during CEA to improve patient care and obtain optimal surgical outcomes.
- Subjects :
- Adrenergic beta-Antagonists
Anesthetics, Local
Angiotensin-Converting Enzyme Inhibitors therapeutic use
Anti-Inflammatory Agents, Non-Steroidal therapeutic use
Anticoagulants therapeutic use
Aspirin therapeutic use
Carotid Stenosis drug therapy
Chemotherapy, Adjuvant
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use
Carotid Stenosis therapy
Endarterectomy, Carotid methods
Subjects
Details
- Language :
- English
- ISSN :
- 1708-5381
- Volume :
- 14
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Vascular
- Publication Type :
- Academic Journal
- Accession number :
- 16956478
- Full Text :
- https://doi.org/10.2310/6670.2006.00020