Back to Search
Start Over
Diagnosis of adenomatous primary aldosteronism in a patient with severe hypertension.
- Source :
-
Nature clinical practice. Endocrinology & metabolism [Nat Clin Pract Endocrinol Metab] 2005 Dec; Vol. 1 (2), pp. 111-5; quiz following 115. - Publication Year :
- 2005
-
Abstract
- Background: A 27-year-old woman presented to her primary-care physician with severe hypertension after complaining of fatigue over the preceding months. She was otherwise asymptomatic. She was referred to a hypertension clinic and was found to be hypokalemic. She was immediately commenced on amlodipine, with atenolol added 2 weeks later. After 4 weeks of this drug therapy, her hypertension persisted and investigations to exclude secondary causes of hypertension were performed.<br />Investigations: Aldosterone and renin levels were measured under controlled conditions and the results expressed as an aldosterone-to-renin ratio. CT of the adrenal glands was also performed.<br />Diagnosis: Adenomatous primary aldosteronism (Conn's syndrome).<br />Management: The patient was initially treated with spironolactone before undergoing a laparoscopic left adrenalectomy.
- Subjects :
- Adrenal Glands diagnostic imaging
Adrenocortical Adenoma drug therapy
Adult
Aldosterone blood
Aldosterone therapeutic use
Algorithms
Humans
Hyperaldosteronism drug therapy
Hypertension drug therapy
Hypokalemia diagnosis
Renin blood
Tomography, X-Ray Computed
Adrenocortical Adenoma complications
Adrenocortical Adenoma diagnosis
Hyperaldosteronism complications
Hyperaldosteronism diagnosis
Hypertension complications
Subjects
Details
- Language :
- English
- ISSN :
- 1745-8366
- Volume :
- 1
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Nature clinical practice. Endocrinology & metabolism
- Publication Type :
- Academic Journal
- Accession number :
- 16929379
- Full Text :
- https://doi.org/10.1038/ncpendmet0047