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Pseudomonas aeruginosa otochondritis complicating localized cutaneous leishmaniasis: prevention of mutilation by early antibiotic therapy.
- Source :
-
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2006 Aug; Vol. 75 (2), pp. 270-2. - Publication Year :
- 2006
-
Abstract
- A patient with an ulcerated cutaneous leishmaniasis of the pinna had suppurative otochondritis after a first unsuccessful course of treatment with meglumine antimoniate. Although the Leishmania ulceration healed after a second course of meglumine antimoniate, and despite three oral dicloxacillin or pristinamycin courses, the otochondritis extended and an abscess developed. Pus from the abscess revealed a pure culture of Pseudomonas aeruginosa. Five days of oral ciprofloxacin plus rifampin led to a marked improvement. The P. aeruginosa isolate was sensitive to ciprofloxacin but fully resistant to rifampin. Healing with minimal mutilation was obtained at the end of a six-week course of multiple antibiotic therapy. Pseudomonas aeruginosa otochondritis was a co-factor of cartilage mutilation in this patient. Thus, infection with P. aeruginosa should be promptly treated when present in tender cutaneous or mucosal leishmaniasis lesions near cartilaginous areas.
- Subjects :
- Adult
Animals
Antimony administration & dosage
Antiprotozoal Agents administration & dosage
Cartilage microbiology
Cartilage parasitology
Cartilage pathology
Ear, External microbiology
Ear, External parasitology
Ear, External pathology
Humans
Immunocompetence
Leishmaniasis, Cutaneous diagnosis
Leishmaniasis, Cutaneous drug therapy
Male
Meglumine administration & dosage
Meglumine Antimoniate
Organometallic Compounds administration & dosage
Pseudomonas Infections diagnosis
Anti-Infective Agents therapeutic use
Ciprofloxacin therapeutic use
Leishmaniasis, Cutaneous complications
Pseudomonas Infections complications
Pseudomonas Infections drug therapy
Rifampin therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9637
- Volume :
- 75
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The American journal of tropical medicine and hygiene
- Publication Type :
- Academic Journal
- Accession number :
- 16896131