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Regulation of enzyme synthesis by the glutamine synthetase of Salmonella typhimurium: a factor in addition to glutamine synthetase is required for activation of enzyme formation.
- Source :
-
Journal of bacteriology [J Bacteriol] 1977 Jun; Vol. 130 (3), pp. 983-90. - Publication Year :
- 1977
-
Abstract
- In Klebsiella aerogenes but not in Salmonella typhimurium glutamine synthetase can function during nitrogen-limited growth to increase the rate of synthesis of histidase from the hut genes of S. typhimurium 15-59 (hutS. 15-59). Formation of proline oxidase is also not increased in nitrogen-limited cultures of S. typhimurium. However, in hybrid strains of Escherichia coli or K. aerogenes, the glutamine synthetase of S. typhimurium activates synthesis of histidase from the hutS. 15-59 genes. Apparently, glutamine synthetase is necessary but not sufficient for activation of transcription of the hut genes; another factor must also be present. This factor is active in both K. aerogenes and E. coli but is missing or altered in S. typhimurium.
- Subjects :
- Amino Acid Oxidoreductases biosynthesis
Enzyme Activation
Escherichia coli enzymology
Genes, Regulator
Genotype
Glutamate-Ammonia Ligase biosynthesis
Histidine Ammonia-Lyase biosynthesis
Klebsiella enzymology
Nitrogen pharmacology
Proline
Enzymes biosynthesis
Glutamate-Ammonia Ligase metabolism
Salmonella typhimurium enzymology
Subjects
Details
- Language :
- English
- ISSN :
- 0021-9193
- Volume :
- 130
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of bacteriology
- Publication Type :
- Academic Journal
- Accession number :
- 16868
- Full Text :
- https://doi.org/10.1128/jb.130.3.983-990.1977