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HTLV-2 infection in injection drug users in King County, Washington.
- Source :
-
Scandinavian journal of infectious diseases [Scand J Infect Dis] 2006; Vol. 38 (8), pp. 654-63. - Publication Year :
- 2006
-
Abstract
- Human T-cell lymphotropic virus type 2 (HTLV-2) is endemic in injection drug users (IDU), and native American populations in the Americas. Transmission is associated with high-risk injection and sexual practices. A cohort of 2561 IDU in King County, Washington completed 2 study visits over 1 y. HTLV-2 infection was detected in 190 (7.4%) of 2561 IDU, and 13 (7.8 cases per 1000 person-y) incident infections occurred during the study. Prevalent infection was associated with female gender, non-white race, longer duration as IDU, having a tattoo, combined injection of heroin and cocaine, and with serologic evidence of hepatitis B and C infection. Seroconversion was more common in women, and was associated with African American race, heterosexual identity and longer duration as IDU. In conclusion, increased risk of HTLV-2 infection was associated with non-white race, and injection drug of choice, suggesting injection networks may play an important role in transmission of HTLV-2. The high correlation of HTLV-2 infection with HCV infection suggests the major route of transmission in IDU is via injection practices. Additional studies are needed to examine the clinical manifestations of HTLV-2 infection, as well as the clinical and virological manifestations of HTLV-2/HCV coinfection.
- Subjects :
- Adolescent
Adult
Female
HTLV-II Infections etiology
HTLV-II Infections transmission
Humans
Incidence
Male
Middle Aged
Needle-Exchange Programs
Prevalence
Risk Factors
Sexual Behavior
Sexually Transmitted Diseases blood
Sexually Transmitted Diseases epidemiology
Washington epidemiology
HTLV-II Infections epidemiology
Human T-lymphotropic virus 2 isolation & purification
Substance Abuse, Intravenous epidemiology
Substance Abuse, Intravenous virology
Subjects
Details
- Language :
- English
- ISSN :
- 0036-5548
- Volume :
- 38
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Scandinavian journal of infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 16857611
- Full Text :
- https://doi.org/10.1080/00365540600617009