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Effect of resection and outcome in patients with retroperitoneal sarcoma.
- Source :
-
ANZ journal of surgery [ANZ J Surg] 2006 Jun; Vol. 76 (6), pp. 462-6. - Publication Year :
- 2006
-
Abstract
- Background: A consecutive series of 47 patients with retroperitoneal sarcoma (RPS) were resected and prospectively followed.<br />Method: Between July 1994 and March 2005, 47 patients (24 men, 23 women; mean age, 56 years; range, 17-82 years) were evaluated.<br />Results: A total of 23 patients had primary RPS and 24 patients had recurrent RPS. A total of 30 out of 47 patients (64%) underwent removal of contiguous intra-abdominal organs. The peroperative mortality was nil and significant preoperative complications occurred in eight cases only (17%). High tumour grade and incomplete resection were significant variables for a worse survival in all 47 patients, both in the univariate and multivariate analyses (P = 0.008 and P = 0.016, respectively). Among 28 radically resected patients, only histological grade affected overall survival (90% 5-year survival for low-grade tumour vs 26% 5-year survival for high-grade tumour; P = 0.006) with a similar effect noted for disease-free survival.<br />Conclusions: Histological grade was the only factor that affected overall and disease-free survival for RPS tumours. An aggressive surgical approach in both primary and recurrent RPS is associated with long-term survival.
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Female
Follow-Up Studies
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Neoplasm Invasiveness
Neoplasm Recurrence, Local pathology
Retroperitoneal Neoplasms pathology
Sarcoma pathology
Survival Rate
Treatment Outcome
Neoplasm Recurrence, Local mortality
Neoplasm Recurrence, Local surgery
Retroperitoneal Neoplasms mortality
Retroperitoneal Neoplasms surgery
Sarcoma mortality
Sarcoma surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1445-1433
- Volume :
- 76
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- ANZ journal of surgery
- Publication Type :
- Academic Journal
- Accession number :
- 16768769
- Full Text :
- https://doi.org/10.1111/j.1445-2197.2006.03753.x