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Influence of testosterone administration on osmoregulation and energy metabolism of gilthead sea bream Sparus auratus.

Authors :
Sangiao-Alvarellos S
Polakof S
Arjona FJ
García-López A
Martín del Río MP
Martínez-Rodríguez G
Míguez JM
Mancera JM
Soengas JL
Source :
General and comparative endocrinology [Gen Comp Endocrinol] 2006 Oct; Vol. 149 (1), pp. 30-41. Date of Electronic Publication: 2006 Jun 12.
Publication Year :
2006

Abstract

The osmoregulatory and metabolic role of testosterone (T) in the euryhaline teleost Sparus auratus was examined. Fish were implanted with a slow-release coconut oil implant alone (control) or containing T (2 or 5microgg(-1) body weight) and sampled 1, 3, and 7 days after implantation. Gill Na(+),K(+)-ATPase activity increased in fish treated with the lower dose of T after 7 days of treatment. Kidney Na(+),K(+)-ATPase activity enhanced at first day post-implantation in the group treated with the higher dose of T but the values diminished by day 3. Plasma levels of metabolites (glucose, lactate, triglyceride, and protein) increased after T treatment. This higher availability of plasma metabolites was reflected in several metabolic changes within different tissues of T-treated fish such as (i) increased glycogen levels and capacity for gluconeogenesis, ketogenesis, glucose exporting, and amino acid catabolism in the liver, (ii) enhanced lipogenic capacity in the gills, (iii) increased glycogen levels and capacity for oxidizing amino acids in the kidney, and (iv) enhanced levels of glycogen, aceotacetate, glucose and triglycerides, and higher capacity of phosphorylating glucose in the brain. These results provide evidence regarding an osmoregulatory and metabolic role for T in S. auratus that could be related to changes in both processes during sexual maturation.

Details

Language :
English
ISSN :
0016-6480
Volume :
149
Issue :
1
Database :
MEDLINE
Journal :
General and comparative endocrinology
Publication Type :
Academic Journal
Accession number :
16765351
Full Text :
https://doi.org/10.1016/j.ygcen.2006.05.003