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Antiarrhythmic activity of taurhythman.
- Source :
-
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2005 Nov; Vol. 140 (5), pp. 529-31. - Publication Year :
- 2005
-
Abstract
- Antiarrhythmic properties of taurhythman were demonstrated on experimental models of ventricular (early occlusion and calcium chloride-induced) and atrioventricular (aconitine-induced) arrhythmias. The preparation reduced or prevented episodes of paroxysmal tachycardia and ventricular fibrillation, decreased the incidence of arrhythmias, and increased the lethal dose (LD) of arrhythmogenic agents. By its efficiency, taurhythman was superior to procainamide and comparable to lidocaine.
- Subjects :
- Aconitine pharmacology
Animals
Anti-Arrhythmia Agents pharmacology
Disease Models, Animal
Heart Arrest
Male
Rats
Tachycardia, Paroxysmal drug therapy
Ventricular Fibrillation drug therapy
Alkanesulfonic Acids pharmacology
Arrhythmias, Cardiac drug therapy
Cardiotonic Agents pharmacology
Lidocaine pharmacology
Procainamide pharmacology
Tachycardia, Paroxysmal prevention & control
Ventricular Fibrillation prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 0007-4888
- Volume :
- 140
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Bulletin of experimental biology and medicine
- Publication Type :
- Academic Journal
- Accession number :
- 16758616
- Full Text :
- https://doi.org/10.1007/s10517-006-0015-5