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Copper-mediated C-N bond formation via direct aminolysis of dithioacetals.
- Source :
-
Organic letters [Org Lett] 2006 Jun 08; Vol. 8 (12), pp. 2547-50. - Publication Year :
- 2006
-
Abstract
- Mediated by copper acetate, an efficient approach to the C-N bond formation via direct aminolysis of dithioacetals 2 and 5 with ammonia, primary or secondary amines are developed under mild conditions. Enaminones 3 and 6 were thus obtained in high to excellent yields with high chemoselectivity. This type of aminolysis reaction presents a new synthetic application of the dithioacetal functionality. [reaction: see text]
Details
- Language :
- English
- ISSN :
- 1523-7060
- Volume :
- 8
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 16737310
- Full Text :
- https://doi.org/10.1021/ol060763c