OFF-off rebound dyskinesia in subthalamic nucleus deep brain stimulation of Parkinson's disease.

Authors :: Brodsky MA
Hogarth P
Nutt JG
Source :: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2006 Sep; Vol. 21 (9), pp. 1487-90.
Publication Year :: 2006
Abstract: A 61-year-old man with Parkinson's disease (PD), motor fluctuations, and dyskinesias underwent bilateral implantation of deep brain stimulation (DBS) electrodes in the subthalamic nucleus (STN). One month after surgery, DBS was optimized to bilateral monopolar settings at the most proximal electrode just superior to the STN, which improved motor fluctuations and dyskinesias. At several postoperative evaluations off medications overnight, both stimulators were turned off and within 60 seconds he developed severe dyskinesias. When the stimulators were turned back on, the dyskinesias soon resolved. This article is a first report of a unique pattern of rebound-type dyskinesia that occurred in the off medication state produced by stopping STN DBS.<br /> ((c) 2006 Movement Disorder Society.)

Language :: English
ISSN :: 0885-3185
Volume :: 21
Issue :: 9
Database :: MEDLINE
Journal :: Movement disorders : official journal of the Movement Disorder Society
Publication Type :: Academic Journal
Accession number :: 16721730
Full Text :: https://doi.org/10.1002/mds.20964

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