Toward the synthesis of the antibiotic branimycin: novel approaches to highly substituted cis-decalin systems.

Authors :: Mulzer J
Castagnolo D
Felzmann W
Marchart S
Pilger C
Enev VS
Source :: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2006 Aug 07; Vol. 12 (23), pp. 5992-6001.
Publication Year :: 2006
Abstract: A variety of highly functionalized cis-decalin systems have been prepared by means of the stereoselective transannular Diels-Alder (TADA) reaction of a (Z,E,Z,Z)-tetraene macrolide, and by means of intramolecular nitrile oxide olefin (INOC) or ring-closing metathesis (RCM) annulations to quinic acid derivatives.

Subjects :: Anti-Bacterial Agents chemistry
Crystallography, X-Ray
Macrolides chemistry
Magnetic Resonance Spectroscopy methods
Models, Molecular
Molecular Conformation
Stereoisomerism
Anti-Bacterial Agents chemical synthesis
Macrolides chemical synthesis
Naphthalenes chemistry

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